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Passive anaphylaxis and IgE antibody production are compromised in tumor necrosis factor- and in granulocyte-macrophage colony stimulating factor-deficient mice
granulocyte-macrophage colony stimulating factor-deficient mice IgE mast cell passive cutaneous anaphylactic reaction tumor necrosis factor-deficient mice
2010/11/25
Background: A number of recent studies has demonstrated a critical role for mast cells and mast cell-derived cytokines, especially tumour necrosis factor (TNF), in the control of host defense mechanis...
Effect of repeated antigen inhalation on airway inflammation and bronchial responsiveness to acetylcholine in interleukin-5 transgenic mice
bronchial hyperresponsiveness eosinophils interleukin-5 mice
2010/11/25
Bronchial hyperresponsiveness (BHR) is a characteristic feature of bronchial asthma, yet its precise mechanism remains obscure. Human studies have demonstrated that T helper 2 cytokines, including int...
EFFECTS OF VITEX AGNUS CASTUS ON MICE FETUS DEVELOPMENT
Vitex agnus castus Mice fetus development
2010/4/20
Vitex agnus castus (chasteberry) is a popular treatment for the management of female reproductive disorders including corpus luteum insufficiency, premenstrual syndrome (PMS), menopausal symptoms, and...
Effects of ultraviolet-inactivated herpes simplex virus type I on atopic dermatitis-like lesions in NC/Nga mice: Role of the suppressor of cytokine signaling in the skin
atopic dermatitis herpes simplex virus suppressor of cytokine signaling (SOCS) Th1 Th2
2010/11/22
Ultraviolet-inactivated HSV treatment would appear to induce a Th1 cellular response and downregulate that of the Th2 pathway in AD-like lesions of NC/Nga mice by bringing about a reduction of SOCS3 e...
The Role of Overproduction of Nitric Oxide in Apoptosis of BALB/C Mice Macrophages Infected with LeishmaniaMajor in Vitro
Nitric Oxide Apoptosis BALB/C Mice Macrophages LeishmaniaMajor
2010/4/26
Nitric oxide (NO) derived from activated macrophages has been shown to be crucial for the host's leishmanicidal activities. Excess NO, however, can in¬duce apoptosis in some cell types, including ...
Serum Levels of Th2-Type Immunoglobulins are Increased in Weanling Mice Subjected to Acute Wasting Protein-Energy Malnutrition
Protein-energy malnutrition Serum immunoglobulins
2010/4/16
The bulk of our knowledge on immunosuppression in malnutrition comes from the experiments done on cell-mediated immunity. However, malnutrition-induced modifications of humoral immunity have been less...
EFFECT OF IMMUNOMODULATOR DARAPRIM ON POTENTIATION OF VACCINE PROTECTION OF LEISHMANIA MAJOR IN BALB/c MICE
Daraprim VACCINE PROTECTION MMUNOMODULATOR
2010/5/4
In this study, a crude leishmanial antigen, was prepared by sonicating Leishmania major promastigotes used to induce immunity in BALB/c mice against cutaneous leishmaniasis. Correlation between the ro...