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pH值和金属离子对尖吻蝮蛇抗凝血因子Ⅱ二级结构的影响(The Effects of pH and Metal Ions on the Secondary Structure of Anticogulation Factor Ⅱ Studed by CD Spectroscopy)
抗凝血因子Ⅱ 酸度(pH) 二级结构 圆二色谱
2010/8/25
圆二色谱(CD谱)测量表明,尖吻蝮蛇抗凝血因子Ⅱ(ACF Ⅱ)与抗凝血因子Ⅰ(ACF Ⅰ)的二级结构十分相似,它们的主要骨架构象都为反平行β-折叠和α-螺旋结构。pH值对天然ACF Ⅱ的构象有一定的影响,pH值从3到10增大时,α-螺旋含量逐渐减少,反平行β-折叠含量逐渐增大。钙和其他二价金属离子对ACF Ⅱ的骨架结构没有明显影响。三价稀土离子使ACF Ⅱ的α-螺旋含量升高,同时降低其β-转角和β...
Determination of the H3 Factor in Hydrogen Isotope Ratio Monitoring Mass Spectrometry
Hydrogen Isotope Ratio Monitoring Mass Spectrometry
2014/4/8
The H3 factor, K, is a parameter required in highprecision, mass spectrometric analyses of hydrogen isotopic abundances. When H2 is used as the sample gas,
R* ) R - Ki2, where R* is the true HD/H2 ra...