搜索结果: 1-15 共查到“有机化学 evaluation”相关记录17条 . 查询时间(0.232 秒)
Evaluation of solid-phase extraction sorbent with ketoimine groups for the preconcentration of benzene and phenolic compounds in water
Modified silica solid-phase extraction SPE
2010/10/18
The applicability of silica gel, modified with ketoimine groups, to solid phase extraction (SPE) was tested. Basic characteristics of the modified silica were determined using elemental analysis, and ...
Synthesis, characterization, antibacterial and antifungal evaluation of some new platinum(II) complexes of 2-phenylbenzimidazole ligands
Antibacterial activity antifungal activity benzimidazole
2010/10/18
A series of platinum(II) complexes of the type [PtL2Cl2] 1, [PtL2I2] 2, [PtL2(oxalato)] 3, and [PtL2(malonato)] 4 (L= 2-phenylbenzimidazole ligands as ``non-leaving groups'') were synthesized and cha...
Synthesis of some new biheterocyclic triazole derivatives and evaluation of their antimicrobial activity
1,2,4-Triazole 1H-indole 1,3,4-thiadiazole
2010/10/15
2-{3-(4-Substitutedbenzyl)-4-[2-(1H-indol-3-yl)ethyl]-5-oxo-4,5- dihydro-1H-1,2,4-triazol-1-yl}-N'-(aryl-methylene)acetohydrazides (5a-g), 4-amino-2-{-(4-substitutedbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-...
Synthesis and evaluation of phenytoin derivatives as anticonvulsant agents
Phenytoin hydantoin anticonvulsant activity
2010/4/9
2,5-Dioxo-4,4-diphenylimidazolidine-1-carboxylic acid (2) was reacted with methyl ester of different amino acids (1a-c) and substituted benzhydrols (3a-b) in pyridine and in the presence of N,N dicycl...
Synthesis and Leishmanicidal Evaluation of Novel 4-Substituted-2,2-Dimethyl-7-(prop-2-ynyloxy)Chromenes
Synthesis chromene leishmanicidal activity
2010/4/9
Substituted 4-chromenes were synthesized via the Grignard coupling reaction of various substituted phenyl- and benzylmagnesium chlorides with 2,2-dimethyl-7-(prop-2-ynyloxy)chroman-4-one (1) in relati...
Novel Analogues of 2-Pyrazoline: Synthesis, Characterization, and Antimycobacterial Evaluation
2-Pyrazolines Sodium salts of N,N-disubstituted dithiocarbamoic acids Antimycobacterial activity
2010/4/16
Fourteen new 1-[(N,N-disubstitutedthiocarbamoylthio)acetyl]- 3-(2-thienyl)-5-aryl-2-pyrazoline derivatives were synthesized by reacting 1-(chloroacetyl)-3-(2-thienyl)-5-aryl-2-pyrazolines and appropri...
Interaction of Mefenamic Acid with Cobalt(II) Ions in Aqueous Media: Evaluation via Classic and Response Surface Methods
Mefenamic acid cobalt Box-Behnken complexation classical method
2010/4/16
Mefenamic acid reacts with cobalt(II) ions in aqueous alkaline medium to form a highly stable deep brown complex at ambient temperature. The complexation process was optimized in terms of pH, temperat...
Synthesis and Antimicrobial Evaluation of Novel Di-triazoles and 4-Arylidene Amino 4,5 Dihydro-1H-[1,2,4] triazole-5-one Derivatives
Triazole-5-one, Schiff base, antimicrobial activity, X-ray
2010/4/16
A series of novel di-[3(thiophen-2-yl-methyl)-4,5-dihydro-1H- [1,2,4]triazole-5-one-4yl]n-alkanes (2a-h) were obtained by the reaction of N'-1-ethoxy-2-thiophen-2-yl-ethylydene hydrazino carboxylic ac...
Short and Effective Synthesis of a Thiophene Analogue of (\pm)-4-Ipomeanol and Its Biological Evaluation
Sonogashira reaction 4-ipomeanol cytotoxic activity MTT assay
2010/4/19
The thiophene analogue of (\pm)-4-ipomeanol (1) was prepared in 2 steps starting from 3-iodothiophene and pent-4-yn-2-ol. The key steps were a Sonogashira reaction, followed by HgO catalysed hydratisa...
Synthesis and Anticancer Evaluation of Some New Unsymmetrical 3,5-Diaryl-4H-1,2,4-Triazole Derivatives
4H-1,2,4-Triazoles 4-Amino-4H-1,2,4-triazoles 4-Arylidenamino-4H-1,2,4-triazoles 4-Arylmethylenamino-4H-1,2,4-triazoles Synthesis Anticancer activity
2010/4/19
A series of 4-arylidenamino-4H-1,2,4-triazole derivatives (3-11) were synthesized from the treatment of 4-amino-4H-1,2,4-triazoles (2) with certain aldehydes. Compounds 3-11 were reduced with NaBH4 to...
Synthesis of Mannich Bases of Some 2,5-Disubstituted 4-Thiazolidinones and Evaluation of Their Antimicrobial Activities
2,5-Disubstituted 4-thiazolidinones synthesis Mannich bases antimicrobial activity
2010/4/20
4-Carbethoxymethyl-2-[(a -chloropropionyl/a -bromobutyryl/a-chloro-(a-phenyl)acetyl)amino]thiazoles (2a-c) were synthesized by the reaction of 4-carbethoxymethyl-2-aminothiazole (1) with a-chloropropi...
Synthesis, Characterization and Primary Antimicrobial Activity Evaluation of 3-Phenyl-6-methyl-4(3H)-quinazolinone-2-yl-mercaptoacetic Acid Arylidenehydrazides
4(3H)-Quinazolinone arylidenehydrazide synthesis antimicrobial activity
2010/4/20
3-Phenyl-6-methyl-4(3H)-quinazolinone-2-yl-mercaptoacetic acid hydrazide (3) was reacted with substituted aldehydes in absolute ethanol to obtain a new series, 3-phenyl-6-methyl-4(3H)-quinazolinone- 2...
Synthesis and Antimicrobial Evaluation of Some New 2-(2-(p-chlorophenyl) benzimidazol-1-yl methyl)-5-substituted amino-[1,3,4]-thiadiazoles
Benzimidazoles thiadiazoles antimicrobial activity X-ray
2010/4/20
Some 2-(2-(p-chlorophenyl)benzimidazol-1-ylmethyl)-5-substituted amino-[1,3,4]-thiadiazoles were synthesized and their in vitro antimicrobial activities were tested against Staphylococcus aureus, Baci...
Direct Dyes Derived from 4,4'-Diaminobenzanilide Synthesis, Characterization and Toxicity Evaluation of a Disazo Symmetric Direct Dye
Direct dyes 4,4'-diaminobenzanilide fastness properties Hydractinia echinata toxicity MRC50
2010/4/20
The synthesis of a new symmetric disazo direct dye containing the non--carcinogenic 4,4'-diaminobenzanilide as the middle component and salicylic acid as the coupling component is presented. The synth...
Synthesis and Evaluation of Antimicrobial Activity of New 3-Hydroxy-6-methyl-4-oxo-4H-pyran-2- carboxamide Derivatives
Chlorokojic acid amide derivatives of pyranone antibacterial activity antifungal activity
2010/4/21
The synthesis of a range of 3-hydroxy-4-oxo-4H-pyran-2- carboxamide with antimicrobial activity is described. Amide derivatives of pyranone were synthesised using TBTU [2-(1H-benzotriazol-1-yl)-1,1,3,...