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中国科学院上海应用物理研究所专利：DNA的荧光检测方法及其试剂盒
中国科学院上海应用物理研究所专利：一种DNA的荧光检测方法及其试剂盒
据美国《每日科学》网站7日报道，上海交通大学樊春海院士及美国亚利桑那州立大学颜颢教授等在最新一期《自然·化学》杂志上发表论文称，他们创建出一种新型元DNA结构，这些元DNA结构可自我组装成形状各异的微米级结构，应用于光电子学及合成生物学领域，从而促进信息存储和加密等技术的发展。研究人员解释，DNA结构的独特特征使其可用作复杂纳米结构和设备的通用组件。借助DNA折叠技术，长的单链DNA（ssDNA）...
High yield DNA fragmentation using cyclical hydrodynamic shearing
High yield DNA fragmentation cyclical hydrodynamic shearing
2016/12/2
We report a new DNA fragmentation technique that significantly simplifies conventional hydrodynamic shearing fragmentation by eliminating the need for sample recirculation while maintaining high fragm...
量子点（ＱＤ）具有抗漂白能力强、量子产率高、激发谱宽和发射谱窄等优点，在生物荧光标记领域有较广泛的应用。利用ＱＤ５８５和Ｈｏｅｃｈｓｔ３３３４２（Ｈ３４２）双标记小鼠卵母细胞中ＤＮＡ甲基转移酶（Ｄｎｍｔ）和染色体，通过双光子成像同时双通道探测它们的荧光图像，获得了Ｄｎｍｔ蛋白表达的三维空间分布。发现老龄小鼠卵母细胞不适合体外培养成熟：该成熟方式不仅引起老龄小鼠卵母细胞Ｄｎｍｔ蛋白含量的变化，而且还...
Nonlinear Optical Studies of DNA Doped Rhodamine 6G-PVA Films Using Picosecond Pulses
DNA Thin Films Z-Scan Picosecond Two-Photon Absorption
2013/1/30
We present our results from the measurements of third-order optical nonlinearity in DNA doped Rhodamine 6G/PVA films achieved through Z-scan measurements using ~2 picosecond (ps) pulses at a wavelengt...
Microfluidic DNA fragmentation for on-chip genomic analysis
Microfluidic DNA fragmentation genomic analysis
2016/12/2
We report a high-throughput clog-free microfluidic deoxyribonucleic acid (DNA) fragmentation chip that is based on hydrodynamic shearing. Salmon sperm DNA has been reproducibly fragmented down to ～ 5k...