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Effect of Shear Stress on RhoA Activities and Cytoskeletal Organization in Chondrocytes
Biomedical Engineering
2015/1/12
Mechanical force environment is a major factor that influences cellular homeostasis and remodeling. The prevailing wisdom in this field demonstrated that a threshold of mechanical forces or deformatio...
Effects of interstitial fluid flow and cell compression in FAK and SRC activities in chondrocytes
FAK Src Mechanotransduction
2015/1/12
Articular cartilage is subjected to dynamic mechanical loading during normal daily activities. This complex mechanical loading, including cell deformation and interstitial fluid flow, affects chondroc...
Apoptosis of Growth Plate Chondrocytes Occurs through a Mitochondrial Pathway
Growth plate Chondrocytes Inorganic phosphate Apoptosis Caspases Endonucleases
2008/11/3
Objective: To determine the role of mitochondria in chondrocyte apoptosis induced by inorganic phosphate (Pi).Materials and Methods: Chondrocytes isolated from the growth plates of chick embryo tibia ...
Time Course of Expression of Bcl-2 and Bax in Rabbit Condylar Chondrocytes Following Forward Mandibular Positioning
Forward mandibular positioning Functional appliance Endochondral ossification Condyle
2008/10/30
Objective: To clarify the expression of Bcl-2 and Bax following forward mandibular positioning (FMP) in the condylar chondrocytes of rabbits.Materials and Methods: Sixty rabbits at 8 weeks of age were...