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A Comparison of Dexmedetomidine, Moxonidine and Alpha-Methyldopa Effects on Acute, Lethal Cocaine Toxicity
Cocaine Intoxication Dexmedetomidine Moxonidine Alpha-Methyldopa
2015/11/6
Background: The treatment of cocaine toxicity is an important subject for emergency physicians. We investigated the effects of dexmedetomidine, moxonidine and alpha-methyldopa on acute cocaine toxicit...
Intravenous Dexmedetomidine Sedation For Spinal Anesthesia in the Prone Knee-Chest Position For Lumbar Laminectomy Surgery
prone position lumbar laminectomy dexmedetomidine
2009/6/23
Lumbar disc hernia is a frequent pathology whose treatment is essentially surgical. Therefore, either general anesthesia with intubation and controlled ventilation or neuraxial blocks such as epidural...
The Effects of Perioperative Low - Moderate Doses of Dexmedetomidine Infusion on Hemodynamic and Neuroendocrine Parameters
Alpha-2 agonist dexmedetomidine autonomic nervous system catecholamine neuroendocrine response
2009/6/16
Aim: The aim of this study was to determine the effects of low and moderate doses of dexmedetomidine infusions by evaluating hemodynamic and neuroendocrine responses in patients undergoing elective tr...
Attenuation of Vasospasm by Dexmedetomidine after Experimental Subarachnoidal Haemorrhage in Rabbits
Dexmedetomidine subarachnoid haemorrhage vasospasm
2009/6/16
Aim:Vasospasm is one of the most important factors that influence the successful treatment of ruptured intracranial aneurysm. We studied if vasospasm following subarachnoidal haemorrhage (SAH) can be ...
Expressions of genes encoding drug-metabolizing enzymes are altered after sevoflurane, isoflurane, propofol or dexmedetomidine anesthesia
genes encoding drug-metabolizing enzymes sevoflurane isoflurane propofol dexmedetomidine anesthesia
2009/5/8
We previously showed that sevoflurane anesthesia affected the expression ratios of 177 of 10,000 genes in multiple organs of rats by microarray analyses. The maximum number of altered genes was dete...
The effects of dexmedetomidine on human neutrophil apoptosis
dexmedetomidine human neutrophil apoptosis
2009/3/2
The purpose of the present study was to evaluate the effect of dexmedetomidine, used as a sedative in the intensive care unit, on human neutrophil apoptosis and superoxide production in vitro. Neutr...