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Penn Study Models How the Immune System Might Evolve to Conquer HIV
Penn Study Models Immune System HIV
2016/8/1
It has remained frustratingly difficult to develop a vaccine for HIV/AIDS, in part because the virus, once in our bodies, rapidly reproduces and evolves to escape being killed by the immune system.“Th...
THERAPEUTIC IMPLICATIONS OF COMPUTER MODELS OF BRAIN ACTIVITY FOR ALZHEIMER DISEASE
COMPUTER MODELS
2015/7/31
Neural models of large-scale brain processes help to explain many features of neuropsychological syndromes and psychiatric disease. Two associative memory models useful to understand some aspects of c...
Punctuated equilibrium in statistical models of generalized coevolutionary resilience: How sudden ecosystem transitions can entrain both phenotype expression and Darwinian selection
coevolution cognitive paradigm gene expression information theory
2015/7/29
We argue, using a mathematical model based on asymptotic limit theorems of probability theory, that mesoscale ecosystem resilience shifts can entrain punctuated events of gene expression and other cog...
Joint models for longitudinal and survival data
joint models longitudinal data survival data bivariate change point models prediction Bayesian method EM algorithm
2015/5/21
Epidemiologic and clinical studies routinely collect longitudinal measures of multiple outcomes. These longitudinal outcomes can be used to establish the temporal order of relevant biological processe...
Variable selection and structural discovery in joint models of longitudinal and survival data
Joint models Mixed effect selection Structural discovery Adaptive LASSO Gaussian quadrature EM algorithm
2015/5/21
Joint models of longitudinal and survival outcomes have been used with increasing frequency in clinical investigations. Correct specification of fixed and random effects, as well as their functional f...
A Note on Adapting Propensity Score Matching and Selection Models to Choice Based Samples
Adapting Propensity Score Matching Selection Models Choice Based Samples
2015/1/22
The probability of selection into a treatment, also called the propensity score, plays a central role in classical selection models and in matching models (see, e.g., Heckman, 1980; Heckman and Navarr...
The aim of this review is to provide the state of the art about the psychology of sport injury rehabilitation by analyzing the most recent literature and research on this field. In the first part we p...
Does the Missing Data Imputation Method Affect the Composition and Performance of Prognostic Models?
Data Multivariable imputation via chained equations Expectation maximum algorithm
2015/9/25
Background: We already showed the superiority of imputation of missing data (via Multivariable Imputation via Chained Equations (MICE) method) over exclusion of them; however, the methodology of MICE ...
Evaluating prediction ability of different models used for solute solubility calculation in binary solvent systems
Binary solvent system Cosolvency Comparison of models
2010/1/6
The available theoretical and empirical models for expression a solute solubility in a binary solvent system as a function of the solvent concentration have been compared by the accuracy and predictab...
Effect of Cryptococcal Capsular Compounds on Blood Coagulation in Animal Models
Glucoronoxylomannan (GXM) Cryptococcus neoformans Blood Coagulation
2010/1/5
Glucoronoxylomannan (GXM) is the most important compound of polysaccharide capsule in Cryptococcus neoformans that causes infection in its recognition as a foreign agent by immune system. Because of i...
A survey on parity progression ratio in Bushehr and specifying factors that are affected it on the basis of multiple logistic regression models in 2005
Fertility Parity Progression Ratios Birth Order Multiple-logistic regression
2009/12/18
Background and Aim:To assess of human force and population’s programming at high level, is very important that we know rates and characteristics of population. Growth of population has direct relation...
Preparation of oligodeoxynucleotide encapsulated cationic liposomes and release study with models of cellular membranes
Gene delivery Antisense oligonucleotide Cationic liposomes Model membrane
2010/4/8
Cationic liposomes are used for cellular delivery of antisense oligodeoxynucleotide (AsODN), where release of encapsulated AsODN is mainly controlled by endocytosis and fusion mechanisms. In this inve...
Lysed Enterococcus faecalis FK-23 (LFK) Suppressing Allergic Responses in Mouse Models
active cutaneous anaphylaxis allergy Enterococcus faecalis eosinophils lactic acid bacteria mouse strains
2010/11/19
Recently, several clinical trials have been published to discuss the possibility of probiotic supplementation, especially some products of lactic acid bacteria such as Lactobacillus and Bifidobacteriu...
Arsenic Trioxide Compound Modulates Multiple Myeloma Phenotypes: Assessment on Cell Line Models
Multiple myeloma Karpas 707 MMP-2 Angiogenesis Apoptosis Cytotoxicity Arsenic trioxide
2010/2/3
Recent evidences suggest that multiple myeloma phenotypes (MMPs) are involved in the infiltration of multiple myeloma-affected marrow foci. In this study, the effects of arsenic trioxide on the invasi...
Antigenicity of proteins found in cow's milk is age dependent. This is primarily due to infants possessing a more permeable intestinal wall than that in adults. Thus infants may acquire cow's milk all...