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观察激活乙醛脱氢酶2(aldehyde dehydrogenase 2,ALDH2)对糖尿病心肌损伤中双孔钾离子通道TASK-1的影响及其对糖尿病心肌损伤的保护作用。方法:将雄性SD大鼠随机分为正常组(N组)、糖尿病4周组(DM4W组)、糖尿病8周组(DM8W组),糖尿病8周组+低浓度乙醇干预组(DM8W+EtOH组)。采用腹腔单次注射链脲佐菌素 (55 mg/kg)复制糖尿病大鼠模型。行心脏超声...
The pass rate of a test item often serves as an index of its difficulty. This posterior index, though easy to obtain and definite, is susceptible to students' learning level. It cannot play a leading ...
Sleep and circadian timing are fundamental biological imperatives in animals and humans, throughout the lifespan. These biological systems can be challenged by pathology, individual choices, and so...
Study aim: Movement control systems are altered by the aging process. Numerous researches have explained the changes that occur with aging, and many of those changes are related to central nervous sys...
Movement control systems are altered by the aging process. Numerous researches have explained the changes that occur with aging, and many of those changes are related to central nervous system (CNS) e...
Internationalisation and diversities in medicine have led to establishment of international standards in medical education in Europe as the free movement of doctors has become a reality. The World F...
双孔钾离子通道是一个膜蛋白家族,广泛分布于可兴奋和不可兴奋细胞中。TASK-3钾离子通道是新发现的一个双孔钾离子通道家族成员,编码374个氨基酸,对细胞凋亡和增殖有重要的作用。在多种肿瘤组织中TASK-3钾离子通道基因呈高表达,并表现出与钾离子通道功能相关的原癌基因特性。

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