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Effect of vitamin D replacement on indexes of insulin resistance in overweight elderly individuals: a randomized controlled trial
HOMA insulin resistance prediabetes IOM RDA high-dose vitamin D
2018/12/13
Background: It is unclear whether and at what dose vitamin D supplementation affects insulin resistance (IR).
Calcium and 1,25-dihydroxyvitamin D3 modulate genes of immune and inflammatory pathways in the human colon: a human crossover trial
1,25-dihydroxyvitamin D3 calcium colon gene expression Western diet
2018/11/29
Background: A high dietary calcium intake with adequate vitamin D status has been linked to lower colorectal cancer risk, but the mechanisms of these effects are poorly understood.
Prospective association between the Dietary Inflammatory Index and mortality: modulation by antioxidant supplementation in the SU.VI.MAX randomized controlled trial
antioxidants Dietary Inflammatory Index inflammation mortality prospective study
2018/11/28
Background: Chronic inflammation is a central mechanism involved in cardiovascular diseases, cancer, diabetes, and chronic respiratory diseases, 4 leading causes of mortality. Diet is a major source o...
Autologous Blood versus Corticosteroid Local Injection for Treatment of Lateral Epicondylosis:A Randomized Clinical Trial
Autologous blood Lateral epicondylosis Steroid injection Treatment
2015/7/10
Objective: The objective of the present single blinded prospective randomized control trial was assessment of efficacy of autologous blood injection versus local steroid injection in treatment of late...
Statistical analysis of clinical trial data using Monte Carlo methods
joint modeling semicompeting risks Bayesian,Minimization randomization test
2015/5/21
In medical research, data analysis often requires complex statistical methods where no closed-form solutions are available. Under such circumstances, Monte Carlo (MC) methods have found many applicati...
Comparison of Neurofeedback and Transcutaneous Electrical Nerve Stimulation Efficacy on Treatment of Primary Headaches:A Randomized Controlled Clinical Trial
Primary Headache Healthcare Providers Neurofeedback Transcutaneous Electrical Nerve Stimulation
2015/10/14
Background: Headache is one of the most prevalent investigated complaints in the neurology clinics and is the most common pain-related complaint worldwide. Stress is a significant factor that causes a...
A Randomized Trial on the Effect of Razavi's Dietary Pattern on the Components of Metabolic Syndrome
Metabolic Syndrome X Obesity Diet therapy
2015/10/12
Background: Metabolic syndrome can cause cardiovascular disease and diabetes in the affected subjects. With 20 to 30% prevalence rate among the adult population of most countries, it is considered a p...
Evaluation of Aggregometery Parameters and Efficacy of Plavix versus Clopidex in Patients Suffering from Ischemic Heart Disease: A Randomized Double Blind Clinical Trial
Diphosphates Clopidogrel Heart Disease
2015/10/10
Background:: Ischemic heart disease is the leading cause of death in most societies. In a pathophysiologic point of view, it chiefly results from the formation of thrombus in coronary arteries which c...
Affordable antibiotic halves the HIV death rate on treatment, DART trial shows
Affordable antibiotic the HIV death rate treatment DART trial
2010/4/21
A safe, cheap and widely available antibiotic could save the lives of thousands of people starting anti-retroviral treatment for HIV in Africa and other developing countries. The findings come from a ...
EFFICACY OF CITALOPRAM IN TREATMENT OF PATHOLOGICAL SKIN PICKING,A RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED TRIAL
Pathological skin picking neurotic excoriation citalopram
2009/12/17
Various studies suggest that selective serotonin reuptake inhibitors (SSRIs) may be useful in treating pathological skin picking (PSP). This study sought to assess effectiveness of citalopram in compa...
Efficacy of Two Streptokinase Formulations in Acute Myocardial Infarction: A Double-Blind Randomized Clinical Trial
Streptokinase Thrombolytic therapy Myocardial infarction
2009/12/17
Background: We sought to evaluate the efficacy and safety of the different trade forms of streptokinase available in our country, namely Heberkinasa (Heberbiotec, Havana, Cuba) and Streptase (Aventis ...
Comparison of Ceftriaxone Plus Weekly Azithromycin or Daily Ofloxacin for Outpatient Treatment of Pelvic Inflammatory Disease:a randomized clinical trial
Pelvic Inflammatory Disease Azithromycin Ofloxacin
2009/12/7
Objective: To compare the efficacy of ceftriaxone plus Ofloxacin or Azithromycin for cases of pelvic inflammatory disease (PID).Materials and Methods: This clinical terial was performed on 180 women w...
Immunohistochemical Expression of C-Erb-B2, Steroid Receptors and Cathepsin-D in Breast Carcinomas: A Clinicopathologic Trial
Breast carcioma cathepsin-D c-erb-B2
2009/6/29
Aim: We investigated the role of c-erb-B2, hormone receptors and cathepsin D in breast carcinoma progression and their correlation with each other. Methods: Forty-six breast carcinoma patients, operat...
A large-scale field trial to evaluate the efficacy of bacillus larvicides for controlling malaria in western Kenya: Study design and methods
bacillus larvicides malaria western Kenya
2010/12/10
Since malaria vaccine development is slow and parasite resistance to anti-malarial drugs is developing rapidly, vector control is still the most practical method for reducing malaria transmission in d...
Randomized, Blinded Trial Comparing Enoxaparin with Unfractionated Heparin in Patients Undergoing Contemporary Percutaneous Coronary Intervention
Enoxaparin Low molecular weight heparin Unfractionated heparin Percutaneous coronary intervention
2010/4/19
Background: This study was designed to examine a unique and low dose use of intravenous enoxaparin in elective percutaneous coronary intervention (PCI) that would be applicable to an unselected popula...