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Although only 10 percent of amyotrophic lateral sclerosis (ALS) cases are hereditary, a significant number of them are caused by mutations that affect proteins that bind RNA, a type of genetic materia...
RNA-binding proteins (RBPs) play important roles in the post-transcriptional control of RNAs. Identify-ing RBP binding sites and characterizing RBP bind-ing preferences are key steps toward understand...
Microtubules have many roles in the cytoskeletal infrastructure. This infrastructure underlies vital processes of cellular life such as motility, division, morphology, and intracellular organization a...
The discovery and isolation of naturally occurring fluorescent proteins, FPs, have provided much needed tools for molecular and cellular level studies. Specifically the cloning of green fluorescent pr...
Antibodies are a family of glycoproteins that bind specifically to foreign molecules (antigens). The binding between antibodies and antigens has high specificity and affinity resulting from various st...
摘要转化生长因子β超家族的细胞因子在细胞生长发育和分化、物质代谢等方面都有极其重要的作用,这种多功效性决定在细胞内必然存在复杂的TGF β信号传导通路。Smad是TGF β超家族信号传导的下游因子,介导TGF β信号从胞质中传入细胞核,特异性调节TGF β靶基因的表达。最近的研究发现与Smad结合的蛋白因子,包括转录因子、活化因子和抑制因子等在Smad特异性识别和调控TGF β靶基因表达的过程中起...
专著信息 书名 A novel NF-(B binding site controls human granzyme B gene transcription. 语种 英文 撰写或编译 作者 Chun-jian huang,Chen Dong,Bing Sun et al 第一作者单位 出版社 Journal of Immunology (2006 in press). 出版地 出版日期 2006...
Trichophyton rubrum (T. rubrum) is an anthropophilic dermatophyte that is distributed worldwide and causes common cutaneous disease such as mycosis. Although several properties of this fungus have bee...
The GST-free recombinant Pacific mackerel parvalbumin was obtained in an electrophoretically pure state. Data from ELISA and inhibition ELISA revealed that the recombinant parvalbumin contains most of...

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