搜索结果: 1-8 共查到“基础医学 mast cell”相关记录8条 . 查询时间(0.135 秒)
DIFFERENTIAL ROLE OF PI-3KINASE p85 (α & β) REGULATORY SUBUNITS IN MAST CELL DEVELOPMENT
Cell cycle -- Regulation Enzymes
2015/5/25
Stem cell factor (SCF) mediated c-Kit signaling, and downstream activation of Phosphatidylinositol-3 Kinase (PI-3K) is critical for multiple biological effects mediated by mast cells. Mast cells expre...
ERK1 AND ERK2 IN HEMATOPOIESIS, MAST CELL FUNCTION, AND THE MANAGEMENT OF NF1-ASSOCIATED LEUKEMIA AND TUMORS
hematopoiesis neurofibroma leukemia
2015/5/25
Neurofibromatosis type 1 is a genetic disease that results from either heritable or spontaneous autosomal dominant mutations in the NF1 gene, which encodes a protein serving, at least in part, to acce...
Effect of Pentoxifylline Administration on Mast Cell Numbers and Degranulation in a Diabetic and Normoglycemic rat Model Wound Healing
Pentoxifylline Mast cells Diabetes Mellitus Wound Healing
2015/9/28
Background: Wound healing is a complicated and integrated process. Researches in the molecular level on human and animal models have indicated several molecular changes related to the effect of diabet...
Gene Expression Profiling of Human Mast Cell Subtypes: An In Silico Study
carboxypeptidase chymase human mast cells microarray transcriptome
2010/11/18
The MC lineage seems to be far from the granulocyte lineages including basophils. CMA1-high MCs (MCTC) and CMA1-low MCs (MCT) can be regarded as differentiated MC subtypes. As such, importance of data...
Stimulatory effect of cytochalasin D on antigen-induced phospholipase D activation in a murine mast cell model (RBL-2H3)
cytochalasin intracellular signal transduction mast cells phospholipase D
2010/11/29
To investigate the possible involvement of cytoskeletal components in antigen (Ag)-mediated activation of phospholipase D (PLD) in rat basophilic leukemia (RBL-2H3) cells, the effects of cytochalasin ...
Differences in mast cell-bound IgE in the nasal epithelial layer and lamina propria
allergic rhinitis IgE immunohistochemistry mast cell nasal mucosa
2010/11/25
Mast cells in the allergic nasal mucosa are reported to have higher concentrations of high affinity type I Fcε receptors (FcεRI) than mast cells in the non-allergic mucosa. IgE binds to FcεRI on mast ...
Human mast cell activation through Fc receptors and Toll-like receptors
adaptive immunity FcεRI FcγRI GeneChip innate immunity mast cell Toll-like receptor 4
2010/11/22
Mast cells express high-affinity IgE receptors (FcεRI) on their surface and can be activated to secrete a variety of biologically active mediators by cross-linking of receptor-bound IgE. Recent studie...
Suplatast Tosilate Inhibits Human Mast Cell Development from Cord Blood Progenitors
cord blood progenitors human mast cells stem cell factor suplatast tosilate
2010/11/19
Background: Localized mast cell accumulation has been reported in a number of human diseases. Suplatast tosilate has been reported to inhibit IL-3-dependent murine mast cell development, and therefore...