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Diclofenac inhibits Kv1.3 and Kir2.1 expressions in human macrophages and affects the membrane potential and foam cell formation
离子通道 膜电位 巨噬细胞 双氯酚酸 细胞分化
2012/8/20
目的分研究双氯芬酸对人巨噬细胞电压依赖性钾通道Kv1.3、内向整流钾通道Kir2.1表达的影响及意义。方法以健康人外周血单核细胞源性巨噬细胞对象,采用Real-time RT-PCR及Western blot技术研究双氯芬酸对Kv1.3和Kir2.1表达的影响;电压敏感染料膜电位标测技术分析膜电位的变化,并用酶荧光化学法检测摄取氧化修饰低密度脂蛋白(OxLDL)的巨噬细胞内胆固醇酯(CE)的构成比...
Expression of complement-related membrane proteins on lymphocytes and alveolar macrophages in bronchoalveolar lavage fluid
alveolar macrophages bronchoalveolar lavage fluid C3b/C4b receptor C3bi receptor decay accelerating factor membrane cofactor protein
2010/11/29
Interstitial lung disease (ILD) can be separated into two groups: (i) that in which the causes are known; and (ii) that in which the etiologies have not been determined. Meanwhile, complement is essen...