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RNA Synthesis in the Tracheal Epithelial Cells of Aging Mice as Revealed by Electron Microscopic Radioautography
RNA synthesis Macromolecular Microscopic radioautography 3H-uridine
2015/7/21
For the purpose of studying the aging changes of macromolecular synthesis in the tracheal epithelial cells of experimental animals, we studied 10 groups of aging mice during development and aging from...
Barrier disruption in STAT6VT transgenic mice as a potential model for atopic dermatitis skin inflammation
STAT6VT transgenic Atopic Dermatitis
2015/5/25
Atopic dermatitis (AD) is a pruritic, chronic inflammatory skin disease with a lifetime prevalence of 10-20% in children and 1-3% in adults, worldwide. In the past three decades, prevalence of the dis...
Exercise-Induced Changes in the Cortical Bone of Growing Mice Are Bone and Gender Specific
mechanical properties pQCT matrix changes
2014/12/4
Fracture risk and mechanical competence of bone are functions of bone mass and tissue quality, which in turn are dependent on the bone's mechanical environment. Male mice have a greater response to no...
High Bone Mass in Mice Lacking Cx37 Due to Defective Osteoclast Differentiation
gap junctions connexin37 osteoclast
2014/12/4
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
Scientists from USC and NYU design a molecule that blocks cancer growth in mice
Scientists from USC NYU design a molecule blocks cancer growth in mice
2014/6/12
A team of researchers from USC and NYU has developed and patented a small molecule that interferes with cancer progression with minimal side effects.
The molecule prevents two critical proteins from ...
Suppressive effects of the Chinese herbal remedy Tripterygium wilfordii Hook f on eosinophilia and IgE hyperproduction in mice
eosinophilia immunoglobulin E Mesocestoides cortii mouse suppression Tripterygium wilfordii
2010/11/25
The effects of chloroform extract of Tripterygium wilfordii Hook f (TWH extract) on eosinophilia and IgE hyperproduction induced by Mesocestoides cortii infection were examined in BALB/c mice. Mice we...
Passive anaphylaxis and IgE antibody production are compromised in tumor necrosis factor- and in granulocyte-macrophage colony stimulating factor-deficient mice
granulocyte-macrophage colony stimulating factor-deficient mice IgE mast cell passive cutaneous anaphylactic reaction tumor necrosis factor-deficient mice
2010/11/25
Background: A number of recent studies has demonstrated a critical role for mast cells and mast cell-derived cytokines, especially tumour necrosis factor (TNF), in the control of host defense mechanis...