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NONINVASIVE MONITORING OF CCl4 INDUCED ACUTE AND CHRONIC LIVER DAMAGE IN RAT BY SINGLE QUANTUM AND TRIPLE QUANTUM FILTERED 23Na MAGNETIC RESONANCE IMAGING
liver damage carbon tetrachloride rat model
2015/5/22
In present study, single quantum (SQ) and triple quantum filtered (TQF) 23Na magnetic resonance imaging (MRI) was used to monitor the severity and progression of CCl4 induced acute and chronic liver d...
Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia
rodent modeling and remodeling osteoblast
2014/12/4
Recent studies demonstrate that bisphosphonates suppress bone resorption by leading to apoptosis of the osteoclast and inhibiting the differentiation to mature osteoclasts. The influence of bisphospho...
Multiscale analysis of morphology and mechanics in tail tendon from the ZDSD rat model of type 2 diabetes
AFM tension nanoscale
2014/12/4
Type 2 diabetes (T2D) impacts multiple organ systems including the circulatory, renal, nervous and musculoskeletal systems. In collagen-based tissues, one mechanism that may be responsible for detrime...
Effect of dithiotheritol on viability of cryopreserved rat hepatocytes
Cryopreservation Dithiotheritol Hepatocytes
2009/11/26
Background: Prolonged storage of cryopreserved isolated hepatocytes is now possible and such cells have been used with success for drug metabolism and toxicity studies. Quality of the cells before cry...
Effects of Cyclosporin A on rat pancreatic b and D cells and glucose levels (An immunocytochemical study)
Cyclosporin A pancreatic islet b cell D cell glucose
2009/7/1
The effects of cyclosporin A (CsA) on rat pancreatic islet b and D cells and plasma glucose levels at doses of 50 mg/kg body weight applied for 20 days were investigated. Fifteen Swiss Albino rats wer...
Permeability of rat IgE across rat aortic endothelial cell is enhanced by histamine
IgE endothelial cells histamine permeability
2010/11/25
On the basis of results from the present study, histamine, acting via H2 receptors, enhances the permeability of rat IgE across the RAEC mono-layer. The increased permeability of endothelial cells ind...