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Effects of kirenol on bovine type II collagen-induced rat lymphocytes in vivo and in vitro
奇壬醇 II型胶原 淋巴细胞 类风湿性关节炎
2012/4/24
目的观察奇壬醇对牛II 型胶原特异性淋巴细胞体内和体外的免疫调节作用，探讨奇壬醇对抗原特异性淋巴细胞的免疫抑制作用机制。方法将Wistar 大鼠随机分为对照组、模型组、奇壬醇组和泼尼松龙组。除对照组外，均复制胶原诱导关节炎大鼠模型，造模当天开始给药。造模30 d 后取脾脏和引流淋巴结，制备单细胞悬液，经体外培养48 h 后，ELISA法检测培养上清中干扰素-γ（IFN-γ）、白介素-10（IL-1...
The Type and Frequency of Infections Occurring in Collagen Tissue Diseases
Collagen tissue diseases Infection Corticosteroid Cytotoxic drugs
2009/6/29
Corticosteroids, widely used in the treatment of collagen tissue diseases, increase the number of neutrophils and decrease the total numbers of lymphocytes, monocytes, eosinophils and basophils. In ad...