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Novel regulation of neuronal genes implicated in Alzheimer disease by microRNA
Alzheimer APP BACE1 microRNA post-transcriptional gene regulation amyloid fetal neurons
2015/5/21
Alzheimer disease (AD) results, in part, from the excess accumulation of the amyloid-β peptide (Aβ) as neuritic plaques in the brain. The short Aβ peptide is derived from a large transmembrane precurs...
EVALUATION OF GENE REGULATION AND THERAPEUTIC DRUGS RELATED TO ALZHEIMER’S DISEASE IN DEGENERATING PRIMARY CEREBROCORTICAL CULTURES
Alzheimer synapse neurodegeneration primary culture memantine
2015/5/21
Alzheimer’s disease (AD) is a neurological disorder defined by the presence of plaques comprised mostly of amyloid-β (Aβ), and neurofibrillary tangles consisting of hyperphosphorylated microtubule ass...
MRI Measures of Neurodegeneration as Biomarkers of Alzheimer's Disease
magnetic resonance imaging (MRI) Alzheimer's disease (AD) mild cognitive impairment (MCI) biomarkers cognitive complaints Alzheimer's Disease Neuroimaging Initiative (ADNI) visual contrast sensitivity
2015/5/21
Alzheimer’s disease (AD) is the most common age-related neurodegenerative disease. Many researchers believe that an effective AD treatment will prevent the development of disease rather than treat the...
NEUROPATHOLOGICAL CHANGES IN THE PDAPP TRANSGENIC MOUSE MODEL OF ALZHEIMER’S DISEASE
Alzheimer's disease immunohistochemistry medal septal nucleus diagonal band of Broca
2010/2/3
Alzheimer’s disease (AD) is a uniquely human disorder. Although the pathogenesis of AD is not fully understood, growing evidence indicates that the deposition of beta-amyloid (Aβ) and the local reacti...