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Involvement of Fibronectin and Matrix Metalloproteinases in Airway Smooth Muscle Cell Migration for the Process of Airway Remodeling
airway remodeling cell migration fibronectin matrix metalloproteinases smooth muscle cells
2010/11/12
The response of bSMC migration to bSMC-conditioned medium increased with time in culture, and fibronectin (FIB) was detected as a chemoattractant for bSMCs in bSMC-conditioned medium by western blot a...
Contribution of Lung Fibroblast Migration in the Fibrotic Process of Airway Remodeling in Asthma
airway remodeling asthma extracellular matrix fibroblast migration
2010/11/17
The total soluble collagen content increased during the fibrotic change of airway remodeling in asthma. Furthermore, migration of fibroblasts may play a key role in this remodeling process, and fibron...
Airway Remodeling in Asthma
airway hyperreactivity airway inflammation airway remodeling Asthma review
2010/11/18
Airway remodeling can be defined as changes in the composition, content, and organization of the cellular and molecular constituents of the airway wall. Airway remodeling is a characteristic feature o...
Mechanisms of Airway Remodeling in Asthma
airway remodeling goblet cells inflammation smooth muscle subepithelial fibrosis
2010/11/18
Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known a...
Airway Remodeling in Asthma and Irreversible Airflow Limitation—ECM Deposition in Airway and Possible Therapy for Remodeling—
bone marrow-derived cells CTGF myofibroblast peripheral airway TGF-β
2010/11/18
Airway remodeling in asthma is characterized by goblet cell hyperplasia, subepithelial fibrosis, and hyperplasia and hypertrophy of airway smooth muscle cells. The airway wall thickness increases beca...
Airway Remodeling and Airway Smooth Muscle in Asthma
airway hyperresponsiveness hyperplasia hypertrophy in vitro in vivo
2010/11/19
Airway remodeling in asthma has been recognized as structural changes of airways such as smooth muscle hypertrophy (an increase in size of airway smooth muscle cells) and hyperplasia (an increase in t...