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近日，空军军医大学唐都医院心血管内科李妍教授团队在生物医学领域权威期刊《Cell Death＆Differentiation》（IF：12.4，JCR：Q1，中科院分区：1区）发表题为 《Lipid overload-induced RTN3 activation leads to cardiac dysfunction by promoting lipid droplet biogenesis》...
2023年2日22日，中南大学湘雅医院肝脏外科周乐杜教授与病理科陶永光教授团队合作在国际著名期刊《Cell Death & Differentiation》（JCR分区Q1，IF=12.07）以论著形式在线发表了题为“The deubiquitinating enzyme UCHL3 promotes anaplasticthyroid cancer progression and metasta...
上海交通大学基础医学院张晶/钟清/夏强课题组在Cell Death & Differentiation发表急性肝损伤和铁死亡的研究成果（图）
肝脏疾病 肝损伤 细胞死亡 脂质活性氧
2022/6/17
肝损伤和细胞死亡是所有肝脏疾病的共同特征。肝移植是终末期肝病的一种既定的治疗方法。然而，由于器官移植的技术特征，肝移植过程中的缺血/再灌注损伤（Hepatic ischemia-reperfusion，I/R）是肝脏外科手术过程中最具有挑战性的问题之一，其可诱发肝细胞损伤进而导致严重的细胞死亡。铁死亡（ferroptosis）作为一种铁离子依赖的新型细胞程序性死亡，以铁稳态（iron homeos...
厦门大学医学院张云武教授团队在Cell Death & Differentiation杂志发表研究成果（图）
厦门大学医学院 张云武教授 Cell Death & Differentiation 杂志发表 研究成果
2020/10/26
近日，厦门大学神经科学研究所张云武教授团队在著名杂志Cell Death & Differentiation上发表题为RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation的最新研究成果。该研究揭示了一条新的调控tau蛋白磷酸化的途径，为治疗ta...
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain
APE1 DNA repair hematopoiesis
2014/12/12
Ape1 is a molecule with dual functions in DNA repair and redox regulation of transcription factors. In Ape1-deficient mice, embryos do not survive beyond embryonic day 9, indicating that this molecule...
Does DNA Methylation Plays a Critical Role in Osteoblastic Differentiation of Mesenchymal Stem Cells (MSCs)?
Mesenchymal Stromal Cells Cell Differentiation Osteoblastic
2015/10/8
Mesenchymal stem cells (MSCs) are characterized by ability to differentiate into several cell types and self-renewability. These stem cells have a limited capacity in cell lineage differentiation incl...
中国医学科学院实验血液学国家重点实验室王建祥课题组在Leukemia期刊上发表"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene"
血液学 国家重点实验室 王建祥 课题组 Leukemia期刊
2012/2/23
中国医学科学院实验血液学国家重点实验室王建祥课题组在在Leukemia期刊发表文章"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.”
ABNORMAL DIFFERENTIATION OF THE CHORION AND ITS RELEVANCE TO THE DEVELOPMENT OF THE CONCEPTUS
ABNORMAL DIFFERENTIATION CHORION ITS RELEVANCE DEVELOPMENT CONCEPTUS
2009/12/31
Thalassemias, because of climatic, geographic and ecological conditions, are the most common among the genetically endemic in Iran, especially m provinces adjacent to the Caspian Sea and the Persian G...
Nasopharyngeal carcinoma:The role of immunohistochemistry and electron microscopy in differentiation between undifferentiated carcinoma and malignant lymphoma:Report of 10 cases and review of literature
Undifferentiated nasopharyngeal carcinoma (UNC) Immunohistochemistry in UNC
2009/12/31
Undifferentiated nasopharyngeal corcinoma is frequently misdiagnosed as large cell malignant lymphoma. The aim of this study is to evaluate the diagnostic role of immunohistochemistry and electron mic...
Breast Carcinoma Showing Neuroendocrine Differentiation Characterized with Ectopic Hormone Production (2 case reports)
Neuroendocrine differentiation ectopic hormone production breast carcinoma
2009/6/29
Neuroendocrine differentiation can be found in benign or malignant lesions of various organ systems. In 1947, Vogler indicated the existence of neuroendocrine cells in mammary tissue (1). Recent studi...
Th17 Cells and Rheumatoid Arthritis -From the Standpoint of Osteoclast Differentiation-
IL-17 IL-23 osteoclast receptor activator of NF-κB ligand (RANKL) rheumatoid arthritis (RA) T cell Th17
2010/11/17
Rheumatoid arthritis is a chronic disease that affects multiple joints. It is considered to be an autoimmune disease in which a T helper (Th)-1 type response has been implicated to play an important p...
Clinical Differentiation between Resistant Asthma and Chronic Bronchiolitis: Testing a Practical Approach
Air trapping Expiratory High-resolution computed tomography Macrolide
2010/4/27
Intractable asthma is a challenging clinical problem. This study was conducted to determine whether a subset of patients with Intractable asthma may be misdiagnosed and have a form of bronchiolitis in...