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EASL Clinical Practice Guidelines:Management of chronic hepatitis B
Hepatitis B virus EASL guidelines Treatment Interferon alpha Nucleoside/nucleotide analogues
2011/4/2
Our understanding of the natural history of hepatitis B
virus (HBV) infection and the potential for therapy of the
resultant disease has improved. Several new and effective
antiviral agents have be...
Comparison of liver histopathology between chronic hepatitis C patients and chronic hepatitis B and C-coinfected patients
chronic hepatitis coinfection HBV HCV histology
2011/4/2
Background:
The aim of the present study was to compare the histological characteristics of livers between chronic hepatitis C (CHC) patients with and without hepatitis B virus (HBV) coinfection.
Me...
Clevudine myopathy in patients with chronic hepatitis B
Clevudine Hepatitis B Adverse effects Myopathy
2011/4/2
Clevudine (L-FMAU) is a thymidine L-nucleoside analogue that was recently introduced for the treatment of chronic
hepatitis B virus infection. Previous studies showed that clevudine has potent and su...
Virological, serological and biochemical outcomes through 3 years of entecavir treatment in nucleoside-naive Chinese chronic hepatitis B patients
Virological biochemical entecavir treatment
2011/4/2
Hepatitis B virus (HBV) infection has a high prevalence
in China. Entecavir has shown superior efficacy over
lamivudine in Chinese nucleoside-naive chronic hepatitis B
(CHB) patients over 48 weeks,...
Monotherapy versus combination therapy for the treatment of chronic hepatitis B
Monotherapy versus therapy the treatment of chronic hepatitis B
2011/4/2
Nucleos(t)ide analogues, active against hepatitis B polymerase, suppress viral replication and improve clinical outcome. However, the emergence of drug-resistant mutants can result in treatment failur...
HBeAg seroconversion as an important end point in the treatment of chronic hepatitis B
HBeAg seroconversion in the treatment of chronic hepatitis B
2011/4/1
During the natural history of chronic hepatitis
B virus (HBV) infection, the loss of serum hepatitis B e
antigen (HBeAg) and the development of anti-HBe antibodies
(HBeAg seroconversion) mark a tra...