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TGF-β Signaling May Play a Role in the Development of Goblet Cell Hyperplasia in a Mouse Model of Allergic Rhinitis
allergic rhinitis epithelial cells Smad TGF-β
2010/11/12
In the mouse model of allergic rhinitis, OVA challenge induced phosphorylation of Smad2 predominantly in epithelial cells in the nasal mucosa. In addition, the administration of an inhibitor of TGF-β ...
Role of IgE in Eosinophilic Otitis Media
bronchial asthma eosinophilic otitis media eosinophils IgE sensory hearing loss
2010/11/12
Eosinophilic otitis media (EOM) is an intractable otitis media characterized by the presence of a highly viscous yellow effusion containing eosinophils. It mainly occurs in patients with bronchial ast...
Nasopharyngeal carcinoma:The role of immunohistochemistry and electron microscopy in differentiation between undifferentiated carcinoma and malignant lymphoma:Report of 10 cases and review of literature
Undifferentiated nasopharyngeal carcinoma (UNC) Immunohistochemistry in UNC
2009/12/31
Undifferentiated nasopharyngeal corcinoma is frequently misdiagnosed as large cell malignant lymphoma. The aim of this study is to evaluate the diagnostic role of immunohistochemistry and electron mic...
Role of neutral endopeptidase in endotoxin-induced bronchial hyperresponsiveness to substance P in guinea pigs
active sensitization bronchial hyperresponsiveness endotoxin histamine neutral endopeptidase substance P
2010/11/29
To investigate effects of endotoxin on allergic airway diseases, we studied bronchial responsiveness to histamine (HI) and substance P (SP) in actively sensitized and non-sensitized guinea pigs 24 h a...