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p16 Expression in Odontogenic Cysts
Cell cycle proteins immunohistochemistry odontogenic tumors
2009/4/2
Background: p16 protein acts as a tumor suppressor and its functional loss seems to be
most frequent genetic alterations in human tumors. Because there is a lack of information, expression of p16 i...
腺样囊性癌(adenoid cystic carcinoma ,ACC) ,又称圆柱瘤,是涎腺常见的恶性肿癌,好发于小涎腺,易局部复发和远处转移。本文应用免疫组化SP 法对36 例腺样囊性癌标本中P16蛋白和增殖细胞核抗原(proliferation cell nuclear antigen , PCNA) 的表达进行检测,并对其与病理分型、临床分期和远处转移的关系进行探讨。