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Demonstration of the role of prostate-specific antigen in semen liquefaction by two-dimensional electrophoresis
prostate-specific antigen semen liquefaction two-dimensional electrophoresis
2009/2/23
Two-dimensional protein profiles of human semen, prostatic fluid, and seminal vesicle fluid were compared to demonstrate changes in the protein composition of human semen before and after liquefac...
Fertility Inhibition In Vitro and Preliminary Antigen Identification
in vitro fertilization anti-sperm antibodies
2009/2/19
Rabbit anti-mouse sperm (MS) Fab fragments have been prepared, which are capable of inhibiting spermzona interaction (both binding and penetration) and sperm-egg fusion in vitro. In cumulus-intact...
Regional variation in macrophage antigen expression by murine epididymal basal cells and their regulation by testicular factors
Epididymis efferent duct ligation F4/80 Mac-i
2009/2/18
Factors controlling the appearance in the epididymis of basal cells and their expression of macrophage antigens were examined by ligating the efferent ducts to prevent the entry of spermatozoa in ad...
Regional variation in macrophage antigen expression by murine epididymal basal cells and their regulation by testicular factors
Epididymis efferent duct ligation F4/80 Mac-i
2009/2/18
Factors controlling the appearance in the epididymis of basal cells and their expression of macrophage antigens were examined by ligating the efferent ducts to prevent the entry of spermatozoa in ad...
HLA-DR antigen and HLA-DRB1 genotyping with nonobstructive azoospermia in Japan
Testis sperm HLA class II antigen
2009/2/18
We previously reported that the HLA-A33, -B13, and -B44 antigens, which are major histocompatibility complex class I molecules, are involved in the susceptibility of nonobstructive azoospermia in ...
Origin of an 84-kDa protein with ABH blood-typing antigen activity in human seminal plasma
p 84 ABO blood group substance lactotransferrin
2009/2/18
In order to investigate the origin of an 84-kDa protein with ABH blood-typing antigen activity (p 84) and its concentration in human seminal plasma, a monoclonal antibody (mAb p 84) was produced....
Measurement of prostate-specific antigen and human glandular kallikrein 2 in different body fluids
prostate-specific antigen human glandular kallikrein 2 body fluids
2009/2/18
It has been demonstrated that prostate-specific antigen (PSA), in spite of its name, can be detected in body fluids and tumors from a variety of organs. Investigations have shown that human glandu...
Molecular characterizations of an intraacrosomal antigen defined by HS-33 monoclonal antibody
Sperm antigen anti-sperm antibodies acrosome reaction
2009/2/17
Among the numerous anti-sperm monoclonal antibodies generated in our laboratory, HS-33 was shown to react with a conserved antigen on the acrosome of spermatozoa from human and mouse. By using ind...
Functional characterization of the primate sperm acrosomal antigen（PSA-63）
Functional characterization primate sperm acrosomal antigen
2009/2/13
Monoclonal antibody (HS-63) raised in mice against human ejaculated sperm, polyclonal antibodies raised in rabbits against the cognate mouse testicular antigen (MSA-63; or Fab) and polyclonal antibodi...
The use of a seminal vesicle specific proteinMHS-5（antigen）for diagnosis of agenesis of vas deferens and seminal vesicles in azoospermic men
Male infertility fructose prostate-specific antigen testicular failure seminal veslcle-speciflc protein
2009/2/13
Azoospermia is the cause of infertility in 8% of infertile male patients. Ten percent of those patients suffer from agenesis of the seminal vesicle (SV) and vas deferens (VD) agenesis. Currently, ...
Human androgen receptor binding to the androgen response element of prostate specific antigen
Human androgen receptor androgen response element prostate specific antigen
2009/2/12
This study examined the in vitro interaction of the human androgen receptor with a putative androgen response element (ARE) in the promoter region of the prostate specific antigen (PSA) gene. To cha...
Response of prostate volume, prostate-specific antigen, and testosterone to flutamide in men with benign prostatic hyperplasia
Treatment benign prostatic hyperplasia flutamide
2009/2/7
Patients diagnosed as having benign prostatic hyperplasia (BPH) had determination of prostate volume (PV), prostate-specific antigen (PSA), and serum testosterone before consideration for entry into...
Androgen-Dependent transcriptional regulation of the prostate-specific antigen gene by thyroid hormone 3,5,3'-L-triiodothyronine
the prostate-specific antigen gene thyroid hormone 3,5,3'-L-triiodothyronine
2008/12/26
Prostate-specific antigen (PSA) is the most useful biomarker for human prostate cancer and may play a role in prostate tumor biology. Androgens, via their receptors, are the major positive regulators ...
Recombinant Adenovirus Mediated Prostate-Specific Enzyme Pro-Drug Gene Therapy Regulated by Prostate-Specific Membrane Antigen（PSMA）Enhancer/Promoter
Cytosine deaminase prostate adenocarcinoma
2008/12/24
Gene directed enzyme pro-drug therapy (GDEPT) is one of the adjuvant therapeutic regimens for advanced prostate adenocarcinoma, and this research intended to explore how to apply targeting therapy o...
Truncated Semenogelin I Binds Zinc and Is Cleaved by Prostate-Specific Antigen
Transglutaminase variant semen prostate-specific antigen fertility reproduction
2008/12/24
Semenogelins I and II are major coagulum-forming proteins in semen, and they are secreted mainly by the seminal vesicles. These proteins bind Zn2+ and act as substrates for prostate-specific anti...