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Reversal of testicular function after prolonged suppression with an LHRH agonist in rhesus monkeys
testicular function prolonged suppression LHRH agonist rhesus monkeys
2009/2/23
Using subcutaneously implanted osmotic pumps, four male rhesus monkeys were continuously infused for 18 months with 100 micrograms/day of [(imBzl)-D-His6-Pro9-NEt]-LHRH (LHRH-A), a potent agonist of...
Stimulation of sperm production by human chorionic gonadotropin after prolonged gonadotropin suppression in normal men
sperm production human chorionic gonadotropin prolonged gonadotropin suppression normal men
2009/2/20
The precise hormonal milieu required for quantitatively normal spermatogenesis in man is unclear. The authors previously have shown that both supraphysiologic dosages of human chorionic gonadotropin...
Prolonged suppression of plasma LH levels in male rats after a single injection of an LH-RH agonist in poly（DL-lactide-co-glycolide）microcapsules
LH-RH agonist biodegradable microcapsules LH PRL rats
2009/2/20
The authors have examined the effects of a subcutaneous injection of the LH-RH agonist D-Trp6-LH-RH formulated in biodegradable poly(DL-lactide-co-glycolide) microcapsules on plasma levels of D-Tr...
Gonadal and pituitary responsiveness of stallions is not down-regulated by prolonged pulsatile administration of GnRH
Equine hypothalamic-pituitary-gonadal axis ref ractoriness
2009/2/17
The objective of this study was to determine if prolonged pulsatile administration of homologous gonadotropin-releasing hormone (GnRH) at therapeutic or 5x therapeutic doses would cause down-regul...
Prolonged Histamine Deficiency in Histidine Decarboxylase Gene Knockout Mice Affects Leydig Cell Function
Steroidogenesis human choriogonadotropin
2008/12/24
The present study focuses on histaminergic regulation of Leydig cell physiology, since limited information is available so far. To evaluate the dependency of Leydig cells on histamine (HA), we pe...