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RNA nanoparticle therapy stops the spread of incurable bone marrow cancer（图）
RNA 纳米颗粒疗法 骨髓癌 肿瘤治疗
2023/6/27
Multiple myeloma is an incurable bone marrow cancer that kills over 100,000 people every year. Known for its quick and deadly spread, this disease is one of the most challenging to address. As these c...
Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body’s wound healing response to various forms of da...
Advances in our understanding and management of sarcomas–rare bone and soft tissue cancers
sarcomas rare bone and soft tissue cancers
2015/4/21
Bone and soft tissue sarcomas are rare, accounting for approximately 1% of all adult solid malignant tumors. Although these cancers are categorised under the same banner of ‘sarcoma’, they in fact rep...
Bone microenvironment and its role in bone metastasis
Bone microenvironment bone metastasis
2015/4/14
Bone is a common site for cancer metastasis. The development of bone metastases represents a serious progression in a patient with cancer, leading to treatment goals changing from curative to palliati...
Function following limb salvage procedures for bone sarcoma
limb salvage procedures bone sarcoma
2015/4/1
Bone sarcomas are the fourth most common cancer in individuals under 25 years. Osteosarcoma is the most common form of sarcoma in this population, with distal femur the most common tumour location. Be...
The biopsy of bone and soft tissue sarcoma is an integral part in the management of patients with these disorders and inadequate, inappropriate or inaccurate non-representative biopsies do lead to poo...
Principles of limb sparing surgery in bone and soft tissue sarcoma
limb sparing surgery in bone soft tissue sarcoma
2015/4/1
The standard for local control of malignant bone and soft tissue tumours has been amputation. Advances in multimodality treatment have seen a shift towards preservation of the limb. Sophisticated tech...
The role of radiology in assessing bone and soft tissue sarcomas encompasses the initial detection and diagnosis of the lesion, staging the lesion both locally and systemically, guiding biopsy of the ...
Nmp4 restricts bone marrow osteoprogenitors and parathyroid hormone induced bone formation in healthy and estrogen depleted female mice
Osteoprogenitor Estrogen depletion
2015/5/21
We have shown that nuclear matrix protein 4 (Nmp4) attenuates the response to intermittent parathyroid hormone (PTH) in healthy and ovariectomized (OVX) female mice using a global knockout of the Nmp4...
Evaluation of Strontium-89 in palliative treatment of widespread and painful bone metastases due to breast and prostate cancer
Evaluation Strontium-89 palliative treatment bone metastases breast prostate cancer
2010/1/5
Treatment of bone metastases comprises over 10% of the workload of a radiation-oncology center. Bone metastases produce severe pain and immobility, necessitate narcotic use, and reduce the quality of ...
I n this paper pour cases of aneurysmal bone cyst are reported and the different etiological factors considered. We believe that aneurysmal bone cyst disease entity with pathologica radiological and c...
NOVEL APPROACH TO IMMUNOTHERAPY FOR EPITHELIAL CANCERS,BONE AND SOFT-TISSUE SARCOMAS
Apoptosis proteins caspase clinical trials cytotoxic T-lymphocytes epithelial cancers gastric cancer antigen osteosarcoma antigen
2009/7/15
The identification of tumor antigens recognized by cytotoxic T-lymphocytes and subsequent clinical trials using peptide immunization have shown tumor regression in advanced malignant melanoma patients...
Unusual Presentation of a Chondromyxoid Fibroma of the Temporal Bone
Chondromyxoid Fibroma Temporal Bone
2009/6/29
Chondromyxoid fibroma (CF) is an uncommon benign primary bone tumor that was first described by Jaffe and Lichtenstein in 1948 (1). CF usually originates from the long bones of young adults, but has b...
Biochemical Bone Markers in Prostate Cancer Patients with Local and Advanced Bone Metastates
Prostate cancer Deoxypyridinoline Bone markers
2009/6/29
In the present study involving patients with bone metastases arising from prostate cancer, we measured urinary deoxypyridinoline (DPD) as a marker of collagen breakdown activity, serum total and bone-...