搜索结果: 1-15 共查到“肿瘤病理学 B cell”相关记录15条 . 查询时间(0.161 秒)
2023年2日22日，中南大学基础医学院肿瘤研究所陶永光研究员与湘雅医院肝脏外科周乐杜教授团队合作在国际著名期刊《Cell Death & Differentiation》（IF=12.07）以论著形式在线发表了题为“The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metast...
浙江大学基础医学院应颂敏、沈华浩教授团队Cell Research发文揭示肿瘤基因组普通脆性位点序列图谱（图）
浙江大学基础医学院 应颂敏 沈华浩教授团队 Cell Research 肿瘤基因组 普通脆性位点序列 图谱
2020/6/23
人类细胞的每一次增殖和分裂，都伴随着全基因组DNA的精确复制。然而，在快速分裂的肿瘤细胞中，DNA复制常常会发生问题，导致染色体产生缺口或断裂。半个世纪前，人们就观察到肿瘤细胞的染色体容易断裂，且常常发生在一些固定的保守区域，被称为普通脆性位点（Common Fragile Sites)。在复制压力存在情况下，普通脆性位点处易发生染色体重排和基因拷贝数变异，造成基因组不稳定。脆性位点的“脆性”导致...
四川大学华西医院曾勇教授、吴泓教授团队在Cell Death & Differentiation上发表研究论文，揭示肝癌转移的新机制
四川大学华西医院 曾勇 教授 吴泓 Cell Death Differentiation 研究论文 肝癌转移 新机制
2019/11/4
近日，华西医院曾勇、吴泓教授团队在Cell Death & Differentiation上发表题为“TXNDC12 promotes EMT and metastasis of hepatocellular carcinoma cells via activation of β-catenin”的科研论文，揭示蛋白二硫键异构酶TXNDC12能够通过促进β-catenin入核行使其转录因子的功能，...
Renal cell carcinoma is the most common neoplasm of the kidney comprised of different histological variants. Chromophobe renal cell carcinoma (ChRCC) is a rare subtype of renal cell carcinoma (RCC) ma...
Cytomorphological Diagnosis of Giant Cell Tumour of Distal End Radius in Elderly Patient
Benign bone tumour Cytology Giant cell tumour
2015/7/10
Giant cell tumours (GCTs) of bone have been described as the most challenging benign bone tumors. It is very unusual for GCT to occur in patients younger than 20 yrs or older than 55 years. GCT is see...
Metastatic Renal Cell Carcinoma in the Sinonasal Region
Sinonasal region Metastatic renal cell carcinoma Diagnosis
2015/7/10
Sinonasal region is an exceptional site for metastatic tumors. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. Clear cell carcinoma is i...
CHEMOTHERAPY AND BIOLOGICAL AGENTS IN THE CLINICAL MANAGEMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA
CHEMOTHERAPY BIOLOGICAL AGENTS
2015/3/20
Historically surgery and subsequently radiotherapy became established as the primary treatments for head and neck
squamous cell carcinoma. The significant incidence of recurrence and metastasis in pa...
FDG PET: Revolution or evolution in the management of non-small cell lung cancer?
Revolution evolution management of non-small cell lung cancer
2015/3/11
Lung cancer is currently the leading cause of cancer-related death in both men and women in most Western countries. In Australia there is a falling incidence in males that is not matched in females, t...
Contemporary management of non-small cell lung cancer in Australia
Contemporary management non-small cell lung cancer Australia
2015/3/11
In 1955, Bromley and Szur reported on 66 patients with a pathologic diagnosis of lung cancer who had been treated with high dose radiotherapy and who had then proceeded to surgery1. In 24 (46.7%) no t...
University of Queensland researchers have discovered an important step in how proteins glue cells together to form healthy tissues, a process that is often disturbed in diseases such as cancer and inf...
Cytotoxic effects of caffeic acid phenethyl ester (CAPE) on the human multiple myeloma cell line
Caffeic acid phenethyl ester (CAPE) multiple myeloma cytotoxicity IL-6
2010/1/11
Aim: Caffeic acid phenethyl ester (CAPE) has cytotoxic, apoptotic, and antiproliferative effects on various tumor cells, and is the most active component of propolis. This study aimed to examine the i...
Investigation of p53 codon72 polymorphism in oral squamous cell carcinoma (SCC) specimens and normal population by PCR
Squamous cell carcinoma Mouth neoplasm Codon Genotype Exon Polymorphism p53 Polymerase chain reaction
2009/12/7
Background and Aim: A single nucleotide polymorphism at codon 72 of the p53 gene alters the p53 protein structure and affects its activity. This polymorphism depends on geographic regions and race. Al...
G2 checkpoint abrogation as a cancer specific,cell cycle disruption
Cell Cycle G2 checkpoint DNA damage Chemo-sensitization Oncogenesis
2009/7/15
The majority of cancer cells are thought to have accumulated the necessary mutations for oncogenesis as a result of disrupting the cell cycle G1 checkpoint, leading to the replication of damaged DNA. ...
The death receptor TRAIL in cancer cell apoptosis
Death receptor Fas TNF-α TRAIL cancer apoptosis
2009/7/15
Apoptosis is a key regulator or tissue homeostasis. Death ligands and death receptors of the tumor necrosis factor (TNF) family play crucial roles in mediating apoptosis. TNF-related apoptosis-inducin...
An Epidemiologic study of Oral and Pharyngeal Nonsquamous Cell Malignant Tumors inKerman province,Iran
Epidemiology Pharyngeal cancer Oral malignant melano-ma Oral sarcoma Minor salivary gland tumor
2010/4/19
Objective: The aim of the present study was to estimate crude and age-standardized incidence rates for oral and pharyngeal nonsquamous cell malignant tumors in Kerman province over a period of 11 year...