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植物表观遗传学，通过遗传，生化，蛋白质组和基因组的手段探索和阐释DNA和组蛋白的表观遗传学修饰原理，及其在基因表达，基因组稳定性中的作用机制。具体关注DNA和组蛋白的表观遗传修饰对染色质的高级结构的影响，和在细胞分子水平对生物发育的作用。我们以拟南芥为主要的模式研究对象，同时也关注表观遗传学在作物和裸子林业植物中的应用。
Causal explanation beyond the gene: manipulation and causality in epigenetics
causation explanation intervention epigenetics methodology observational studies causalidad explicación intervención epigenética metodología estudios observacionales
2016/5/27
This paper deals with the interrelationship between causal explanation and methodology in a relatively young discipline in biology: epigenetics. Based on cases from molecular and ecological epigenetic...
This thesis is aimed at creating a pipeline for analyzing DNA methylation epigenetics data and creating a data model structured well enough to store the analysis results of the pipeline. In addition t...
Hereditary Hourglass.Genetics and Epigenetics,1868-2000
Hereditary Hourglass Genetics Epigenetics
2015/3/26
Hereditary Hourglass.Genetics and Epigenetics,1868-2000.
Epigenetics mechanisms and degenerative diseases
Epigenetics DNA Methylation Histone Modifications DNA Methylation Rheumatoid Arthritis
2013/1/30
Epigenetic regulations are heritable changes in gene expression that occur in the absence of alterations in DNA sequences. Various epigenetic mechanisms include histone modifications and DNA methylati...
Evolutionary History and Biology, Epigenetics and Ecological Continuum between Geophagia and Health
Evolutionary History Biology Epigenetics Ecological Continuum Geophagia Health
2012/3/14
Evolutionary History and Biology, Epigenetics and Ecological Continuum between Geophagia and Health.
Diabetes—Role of epigenetics,genetics,and physiological factors
epigenetics miRNAs genetics genome wide association
2009/10/12
Diabetes—Role of epigenetics,genetics,and physiological factors。
Epigenetics in Male Germ Cells
Epigenetics Male Germ Cells
2008/12/24
We provide an overview of epigenetic mechanisms comprising DNA methylation, histone modification, and RNA-associated silencing of gene expression by noncoding RNAs and subsequently focus attention...
摘要
科学的发展孕育着突破，表遗传学研究推动着新一轮的遗传学的发展。表遗传学是研究没有DNA序列变化的、可遗传的表达改变。表遗传学不仅对医学和农业有重要的实践意义，而且还提供了理解遗传和进化的新观点。研究表明，人类基因组含有两类遗传信息，遗传学信息提供了合成生命所必需蛋白质的模板，而表遗传学信息提供了何时、何地和怎样地应用遗传学信息的指令；遗传学和表遗传学的关系有如“阴阳”，它们既相区别又协同参...