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北肿团队PD-1/CTLA-4双抗联合化疗一线治疗晚期胃癌1b/2期研究成果（COMPASSION-04）荣登Nature Medicine（图）
晚期胃癌 肿瘤医院 单抗联合化疗
2024/7/10
北京大学肿瘤医院季加孚教授、李子禹教授及沈琳教授共同通讯在国际医学期刊《自然医学》(Nature Medicine)在线发表题为“Cadonilimab with chemotherapy in HER2-negative gastric or gastroesophageal junction adenocarcinoma: the phase 1b/2 COMPASSION-04 trial”...
2023年4月5日，中南大学湘雅三医院泌尿外科王龙教授和美国休斯顿大学Chandra Mohan教授合作在BMC Medicine（中科院一区，IF=11.15）以论著形式线上发表了题为“Comprehensive Proteomics and Platform Validation of Urinary Biomarkers for Bladder Cancer Diagnosis and St...
Nuclear Explained – Nuclear Medicine and Radiation Technologies to Fight Against Cancer
癌症 核医学 辐射技术
2023/3/16
What does nuclear and radiation have to do in the fight against cancer? In this episode, experts explain the key role of radiation-based technologies in comprehensive cancer control.
近日，中南大学湘雅三医院张国刚教授团队在国际权威学术期刊《BMC Medicine》 （IF=11.15，中科院一区）上在线发表原创文章，题为“Associations between consumption of three types of beverages and risk of cardiometabolic multimorbidity in UK Biobank participan...
儿童肿瘤科张渝博士在Nature Medicine发表研究成果（图）
肿瘤科 肿瘤免疫治疗 胆固醇 肿瘤代谢
2023/2/28
近年来，肿瘤免疫治疗频繁取得突破性进展，例如，像PD1/CTLA4类的免疫检查点抑制剂对大约10-35%的实体肿瘤患者有效。过继性TIL细胞回输治疗对20-25%晚期黑色素瘤患者有效。细胞治疗，包括CAR-T和TCR-T细胞治疗，通过改造T细胞使其可以特异性得识别并杀伤肿瘤细胞。但是，细胞治疗对绝大部分实体瘤患者效果欠佳，CAR-T疗法仅在部分血液系统肿瘤中效果显著。
2022年6月1日，上海市第一人民医院眼科中心孙晓东教授团队在转化医学国际顶级期刊Science Translational Medicine杂志发表了题为"Targeting C3b/C4b and VEGF with a bispecific fusion protein optimized for neovascular age-related macular degeneration th...
2022年2月4日，北京大学基础医学院邓宏魁研究组、中国医学科学院/北京协和医学院彭小忠研究组和天津市第一中心医院沈中阳研究组合作在Nature Medicine发表题为Human Pluripotent Stem Cell-derived Islets Ameliorate Diabetes in Nonhuman Primates的研究论文，该研究首先在原有工作基础上进一步优化和改进了人多能干...
颅内动脉瘤（Intracranial aneurysm，IA）是一种人群内发病率较高的疾病，占到普通人群的2-3%，同时颅内动脉瘤每年破裂出血率为1.9%。破裂动脉瘤出血是引起蛛网膜下腔出血（Subarachnoid hemorrhage，SAH）的主要原因，出血导致直接脑损害以及迟发的脑缺血，因而该疾病致死率和致残率极高。据报道，大约三分之一的SAH患者死亡，三分之一的幸存者亦多有残疾或明显的神...
2021年7月27日，上海交通大学医学院上海市免疫学研究所苏冰课题组与合作者在Cell Press细胞出版社期刊Cell Reports Medicine杂志发表题为“Single-cell transcriptomic landscape reveals tumor specific innate lymphoid cells associated with colorectal cancer ...
Challenges and Solutions for Future Pharmacy Practice in the Era of Precision Medicine
Challenges Solutions Future Pharmacy Practice
2018/11/22
As precision medicine research and its clinical applications continue to advance, it is critical for pharmacists to be involved in these developments to deliver optimal, tailored drug therapies for pa...
Evaluation of an Evidence-Based Medicine Curriculum in a PGY1 Pharmacy Residency Program Using the Fresno Test
Evaluation Evidence-Based Curriculum
2018/11/22
Objective. To assess the effectiveness of a longitudinal evidence-based medicine (EBM) curriculum to improve pharmacy resident knowledge and skills in evidence-based practice as measured by the Fresno...
EXTRACTION AND ANALYSIS OF TRADITIONAL CHINESE MEDICINE CROPS BASED ON MULTITEMPORAL HIGH RESOLUTION DATA-TAKING QIAOCHENG DISTRICT OF BOZHOU AS AN EXAMPLE
Multitemporal Remote SensingData Chinese Medicine Crops Interpretation Information Extraction
2018/5/16
Remote sensing technology has become an important method to rapidly acquireing of planting layout and composition of regional crops.It is very important to accurately master the planting area of Chine...
A Qualitative Study Identifying Key Components to Standardize Across Inpatient General Medicine Advanced Pharmacy Practice Experiences
Qualitative Study Components Standardize
2018/11/21
Objective. To identify common components of inpatient general medicine advanced pharmacy practice experiences (APPEs) across sites, determine which components were important to standardize, and distin...
Orthopaedic Knowledge Update: Sports Medicine 5
Orthopaedic Knowledge Update Sports Medicine
2018/4/24
DESCRIPTION
The Orthopedic Knowledge Update series has long been the foundational source of efficient review for all aspects of orthopedic surgery. This book covers the subspecialty of sports medicin...
The idea of uniform change: is it time to revisit a central tenet of Rose’s “Strategy of Preventive Medicine”?
sick populations Geoffrey Rose high risk population strategy uniform change dispersion inter-individual inequality
2018/12/19
A mean-centric view of populations, whereby a change in the mean of a health variable at the population level is assumed to result in uniform change across the distribution, is a core component of Geo...