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Transcriptome profiling from adipose tissue during a low-calorie diet reveals predictors of weight and glycemic outcomes in obese, nondiabetic subjects
obesity insulin resistance low-calorie diet transcriptome analysis adipose tissue
2018/11/19
Background: A low-calorie diet (LCD) reduces fat mass excess, improves insulin sensitivity, and alters adipose tissue (AT) gene expression, yet the relation with clinical outcomes remains unclear.
Transcriptome profiling from adipose tissue during a low-calorie diet reveals predictors of weight and glycemic outcomes in obese, nondiabetic subjects
obesity insulin resistance low-calorie diet transcriptome analysis adipose tissue
2018/11/16
Background: A low-calorie diet (LCD) reduces fat mass excess, improves insulin sensitivity, and alters adipose tissue (AT) gene expression, yet the relation with clinical outcomes remains unclear.
Long-term weight-loss maintenance in obese patients with knee osteoarthritis: a randomized trial
weight loss maintenance diet obesity knee osteoarthritis low-energy diet weight cycling body composition blood pressure
2018/11/16
Background: A formula low-energy diet (LED) reduces weight effectively in obese patients with knee osteoarthritis, but the role of LED in long-term weight-loss maintenance is unclear.
Long-term weight-loss maintenance in obese patients with knee osteoarthritis: a randomized trial
weight loss maintenance diet obesity knee osteoarthritis low-energy diet weight cycling body composition blood pressure
2018/11/19
Background: A formula low-energy diet (LED) reduces weight effectively in obese patients with knee osteoarthritis, but the role of LED in long-term weight-loss maintenance is unclear.
Verification of Maximal Oxygen Uptake in Obese and Nonobese Children
FITNESS VALIDATION TEST PEDIATRIC OBESITY CARDIORESPIRATORY AEROBIC CAPACITY
2018/4/24
Purpose The purpose of this study was to examine whether a supramaximal constant-load verification test at 105% of the highest work rate would yield a higher V˙O2max when compared with an incremental ...
Vitamin D supplementation has no effect on insulin sensitivity or secretion in vitamin D–deficient, overweight or obese adults: a randomized placebo-controlled trial
insulin secretion insulin sensitivity obesity random-ized trial RCT, vitamin D
2018/11/14
Background: Vitamin D supplementation has been proposed as a potential strategy to prevent type 2 diabetes. Existing clinical trials have been limited by short duration, low doses of vitamin D, variab...
Changes in Gait over a 30-min Walking Session in Obese Females
TREADMILL OBESITY WEIGHT LOSS BIOMECHANICS WOMEN FATIGUE
2018/4/24
Purpose This study assessed the biomechanical gait changes in obese and normal-weight female adult subjects after a commonly recommended 30-min walking session. Hip and knee adduction and extensor mom...
Changes in skeletal muscle and organ size after a weight-loss intervention in overweight and obese type 2 diabetic patients
type 2 diabetes magnetic resonance imaging body composition skeletal muscle organ mass weight loss Look AHEAD trial
2018/11/12
Background: The effect of a weight-loss intervention on the masses of lean tissues and organs in humans is not well known.Objective: We studied the effects of a diet and exercise weight-loss intervent...
Diet-induced weight loss improves not only cardiometabolic risk markers but also markers of vascular function: a randomized controlled trial in abdominally obese men
abdominal obesity cardiometabolic risk dietary weight loss flow-mediated vasodilation vascular function
2018/11/12
Background: Many trials assessing effects of dietary weight loss on vascular function have been performed without no–weight loss control groups and in individuals with obesity-related morbidities. Usu...
Effect of weekly physical activity frequency on weight loss in healthy overweight and obese women attending a weight loss program: a randomized controlled trial
physical activity pattern obesity weight loss diet waist circumference cardiometabolic disease risk
2018/12/18
Background: The effect of intensity and duration of physical activity (PA) on weight loss has been well described. However, the effect of the frequency of weekly PA on weight loss is still unknown.
Gut permeability is related to body weight, fatty liver disease, and insulin resistance in obese individuals undergoing weight reduction
obesity liver steatosis insulin resistance intestinal permeability gut barrier
2018/11/12
Background: Obesity and associated metabolic disorders are related to impairments of the intestinal barrier.
Objective: We examined lactulose:mannitol (Lac:Man) permeability in obese individuals with...
Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults
insulin resistance leucine muscle mass inflammation amino acid transporters mTORC1
2018/12/14
Background: Excess body fat diminishes muscle protein synthesis rates in response to hyperinsulinemic-hyperaminoacidemic clamps. However, muscle protein synthetic responses after the ingestion of a pr...
Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults
insulin resistance leucine muscle mass inflammation amino acid transporters mTORC1
2018/12/18
Background: Excess body fat diminishes muscle protein synthesis rates in response to hyperinsulinemic-hyperaminoacidemic clamps. However, muscle protein synthetic responses after the ingestion of a pr...
Beneficial effect of high energy intake at lunch rather than dinner on weight loss in healthy obese women in a weight-loss program: a randomized clinical trial
dinner insulin resistance lunch obesity weight-loss diet
2018/12/14
Background: The association between the time of nutrient intake and health has been described in a few studies. To our knowledge, no study has evaluated the relation between high energy intakes at lun...
Beneficial effect of high energy intake at lunch rather than dinner on weight loss in healthy obese women in a weight-loss program: a randomized clinical trial
dinner insulin resistance lunch obesity weight-loss diet
2018/12/18
Background: The association between the time of nutrient intake and health has been described in a few studies. To our knowledge, no study has evaluated the relation between high energy intakes at lun...