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Inhibitory effect of calotropis gigantea extract on ovalbumin-induced airway inflammation and arachidonic acid induced inflammation in a murine model of asthma
arachidonic acid Calotropis gigantea ovalbumin
2015/7/21
The root of Calotropis gigantea has been reported as a traditional folkloric medicine in treatment of asthma in the Indian literature. Root contain α-and β-amyrin are reported to possess anti-lipoxyge...
Development of Gut Microbiota in a Mouse Model of Ovalbumin-induced Allergic Diarrhea under Sub-barrier System
Ovalbumin BALB/c mice Allergy Diarrhea Gut Microbiota
2016/5/11
This study aimed to present a mouse model of ovalbumin (OVA) induced allergic diarrhea under a sub-barrier system and investigate the development of gut microbiota in this model. Male BALB/c mice were...
Amphiregulin Is Not Essential for Ovalbumin-Induced Acute Airway Inflammation in Mice
amphiregulin asthma EGF IgE mast cells
2010/11/12
Background: The number of amphiregulin (AR)-positive mast cells in the bronchial mucosa and the levels of AR in sputum from asthmatic patients have been reported to be increased. In addition, AR can p...
Production and Characterization of Monoclonal Anti-Ovalbumin Antibodies
Ovalbumin monoclonal antibody hybridoma
2009/6/30
In this study, the results of anti- ovalbumin (OVA) monoclonal antibody production and characterization are reported. Splenocytes from OVA-hyperimmune Balb/C mouse were fused with F0 myeloma cells an...
Effects of L-Ascorbic Acid and Superoxide Anion Radical on the Polymerization of Ovalbumin
L-ascorbic acid superoxide anion radical ovalbumin
2009/6/18
L-Ascorbic acid (AsA) plays an important role in food, especially in the rheological properties of bread dough. So in this study, we estimated the effect of AsA on the polymerization of proteins using...
Increased Number of CCR4-positive Cells in the Duodenum of Ovalbumin-induced Food Allergy Model NC/jic Mice and Antiallergic Activity of Fructooligosaccharides
antiallergic activity CCR4- and CCR5-positive cells food allergy fructooligosaccharides prebiotic food
2010/11/18
The number of CCR4-positive cells increased significantly in Group 2 as compared with Group 1 and tended to decrease in Group 3 as compared with Group 2. Relatively few CCR5-positive cells were observ...
Reduced Serum Antibody Production and Acute Airway Inflammation in Interleukin 6-deficient Mice Challenged with Ovalbumin
animal asthma cytokine eosinophil IL-6
2010/11/19
Background: IL-6 is a unique cytokine that has pro- and anti-inflammatory property. The purpose of this study was to clarify the role of IL-6 in the allergic airway inflammation.
Methods: We challeng...