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Production of Recombinant Alpha Neurotoxin of Scorpion Venom Mesobuthus eupeus and Analysis of its Immunogenicity
Venoms Neurotoxin Scorpion Recombinant Protein
2015/10/10
Background:: Scorpion venom is important and rich source of peptides, most of which have been widely used as pharmacological tools for unraveling structure-function relationship of various ion channel...
Transcriptome analysis of the Tityus serrulatus scorpion venom gland
Scorpions Antimicrobial Peptides Neutoxins Venom Glands Brazilian Yellow Scorpion
2013/1/30
The Tityus serrulatus scorpion is considered the most dangerous scorpion in Brazil and is responsible for several cases of human envenomation annually. In this study, we performed transcriptome profil...
Sequence Analysis of Lysozyme C from the Scorpion Mesobuthus Eupeus Venom Glands Using Semi- Nested RT-PCR
C-type lysozyme Scorpion Mesobuthus eupeus Antimicrobial protein
2015/9/24
Background: Lysozyme is an antimicrobial protein widely distributed among eukaryotes and prokaryotes and take part in protecting microbial infection. Here, we amplified cDNA of MesoLys-C, a c-type lys...
GENETIC ASPECT OF VENOM ALLERGY:ASSOCIATION WITH HLA CLASS I AND CLASS II ANTIGENS
genetic human leukocyte antigens hymenoptera
2010/12/22
Stings from bees and wasps can cause systemic allergic reactions in sensitized patients. However, the mystery of why some cases develop allergic reactions while others do not, remains poorly understoo...
蛇毒蛋白(SNAKE VENOM)
蛇毒蛋白 生物制品 心血管病 治疗药
2008/10/9
蛇毒既用作神经系统基础理论研究的工具药，又是治疗心脑血管疾患的良药，该校可提供制备高纯度蛇毒蛋白(包括银环蛇毒和金环蛇毒)的新工艺和成品。合作方式：技术转让或联合开发。
CATFISH STINGS AND THE VENOM APPARATUS OF THE AFRICAN CATFISH CLARIAS GARIEPINUS (BURCHELL, 1822), AND STINGING CATFISH HETEROPNEUSTES FOSSILIS (BLOCH, 1794)
freshwater catfi sh stings envenomation
2010/12/23
The ability of catfi sh to infl ict extremely painful wounds with their pectoral and dorsal stings has been well known for many decades. The venom apparatus of the African catfi sh Clarias gariepinus ...
银环蛇心脏毒素类似物cDNA的克隆Cloning and Characterization of cDNAs of Cardiotoxin-likeProtein in Bungarus multicinctus Venom Gland
心脏毒素类似物 银环蛇 全长cDNA
2008/1/16
摘要采用SMART技术和RT-PCR方法，从同一个银环蛇毒腺中克隆到了5 种尚未报道过的心脏毒素类似物全长cDNA序列（MNCTL1-a、MNCTL1-b、MNCTL1-c、MNCTL1-d和MNCTL2）。5种序列中，MNCTL1-b、MNCTL1-c、MNCTL1-d和MNCTL2的长度均为505 bp，包括5′非翻译区32 bp，3′非翻译区212 bp和其余261 bp组成的一个完整开放阅...
Systemic and Local Reactions of Bee Venom Immunotherapy in Iran
Anaphylactic Bee venum Cluster Immunotherapy Hymenoptera Reactions
2010/4/29
Severe allergic reactions during specific immunotherapy may occur in the treatment of hymenoptera sting allergy. The objective of the present study was to examine the characteristics of allergic react...
pH值和钙离子对尖吻蝮蛇抗血小板凝集素二级结构的影响（Effects of pH Value and Ca2+ Ion on the Secondary Structure of Agkisacutacin from Agkistrodon Acutus Venom）
抗血小板凝集素 二级结构 圆二色谱 拉曼光谱 红外光谱
2010/8/25
尖吻蝮蛇毒中抗血小板凝集素是凝血因子IX/凝血因子X结合蛋白，它具有抗凝血和抑制血小板凝集双重活性。用红外光谱、拉曼光谱和CD谱研究了抗血小板凝集素的二级结构以及pH值和钙离子对其二级结构的影响。用CD谱测得，在水溶液中，抗血小板凝集素的主要骨架构象为β-折叠(26.3%)和α-螺旋(19.6%)结构。拉曼光谱显示，在粉末状态，其α-螺旋含量显著降低。CD谱还表明，抗血小板凝集素在pH值3.0～1...
Osteopontin: A Potential Biomarker for Successful Bee Venom Immunotherapy and a Potential Molecule for Inhibiting IgE-mediated Allergic Responses
biomarker clustering mechanism microarray osteopontin (OPN) venom immunotherapy (VIT)
2010/11/19
Venom immunotherapy (VIT) is proven to be curative for insect allergy, but the mechanisms and the biomarkers associated with clinical efficacy remain elusive. We report herein the discovery of a leadi...
Morphological, Hemipenial and Venom Electrophoresis Comparisons of the Levantine Viper, Macrovipera lebetina (Linnaeus, 1758), from Cyprus and Southern Anatolia
Macrovipera lebetina hemipenes venom electrophoresis Cyprus southern Anatolia
2010/3/26
Levantine vipers, Macrovipera lebetina (Linnaeus), from Cyprus and southern Anatolia were investigated comparatively regarding morphology, hemipenes and electrophoresis patterns of venom proteins. The...
A novel venom protein of the Asian bee (Apis cerana indica) with an affinity to human α1-microglobulin
α1-microglobulin Asian bee bee venom inflammatory reaction
2010/11/29
Bee stings are a common health problem throughout the world and can sometimes result in fatal anaphylactic reactions. We have studied Asian bee (Apis cerana indica, Apis cerana nigrocincta and Apis do...
A Morphological Study on the Venom Apparatus of Spider Larinioides Cornutus (Araneae, Araneidae)
Larinioides cornutus venom gland morphology chelicerae scanning electron microscope (SEM)
2010/3/29
The morphological structure of the venom apparatus of Larinioides cornutus was studied using a scanning electron microscope(SEM). The Venom glands are situated in the anterior cephalic part of the pro...
In Vitro Assessment of Bee Venom Effects on Matrix Metalloproteinase Activity and Interferon Production
Bee Venom Fibrosarcoma Interferon Matrix Metalloproteinase Monocyte
2010/2/3
Controversial immunomodulatory properties of bee venom (BV) have provided an appropriate field for more investigation. The aim of present research was to verify the effects of honeybee venom on matrix...
A Morphological Study on the Venom Apparatus of the Spider Agelena labyrinthica (Araneae, Agelenidae)
Spider Agelena labyrinthica venom apparatus morphology SEM (scanning electron microscopy )
2010/3/29
The morphology of the venom apparatus of the spider Agelena labyrinthica was studied using scanning electron microscopy. The venom apparatus, situated in the anterior of the prosoma, is composed of a ...